With respect to the last question, circular mature viroid RNAs have been proposed as the prevalent RNA substrates of the DCLs generating the vd-sRNAs from two nuclear replicating viroids [38], [40], but more complex scenarios can be also envisaged considering the nuclear co-localization of viroid replication and part of the RNA silencing machineries.
To test this, the following scenario may be envisaged: consider the known distribution of a given mammal from the list; select spatial cells at random from this distribution; in each cell capture the chosen mammal species and test for the presence of Leishmania.
If you find some things are taking a lot more time than you originally envisaged, consider whether a change in approach will be adequate or whether it is something you are always going to find a bit of a battle.
Consequently, even better hybrid methods may be envisaged by considering even larger feature spaces.
As an extension of this study, a hierarchical model could be envisaged, by considering macro socio-economical variables relevant to the regions; this may improve the part of explained variance of the latent trait.
Finally, DETC therapy might also be envisaged in visceral leishmaniasis, considering the higher morbidity/mortality and more frequent therapeutic complications of, this clinical form, especially in the case of HIV co-infection, which is of increasing epidemiological importance in Southern Europe and Latin America [1] [4].
Gene expression profiling serves as an appropriate strategy to unravel the underlying signatures to envisage such varied responses and considering this, gene transcription profiling was examined in control and TNFα treated HepG2 cells.
A wide range of applications can be envisaged when we consider more complex donor arrangements.
In the present application of the model to nonpremixed combustion, mixture fraction is considered as the scalar; extensions of the model may be envisaged for other combustion modes by considering a different scalar variable.
Now we can envisage an intelligent being creating such worlds, but, through considering their features, we can articulate some marks of purposive design to help us judge whether the cosmos was designed rather than created at random.
