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All current cultivars used for delayed planting were selected under environments of normal planting.
That was mainly due to the complicated cardiotoxicity mechanism of DOX which results in the totally different membrane environments of normal and pathological myocardium in vivo.
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Throughout the long process of transformation, the cell resides in an environment of normal neighbors and is exposed to their influence, which could be pro- and anti-carcinogenic.
Thus, whilst experimental data have shown that direct injection of viral vector into normal rabbit IVDs leads to synthesis of gene product and increased production of proteoglycans [ 48], the increased nutrient and oxygen transfer into IVD tissue, the cytokine and eicosanoid load and the growth factor environment of normal animal IVDs are markedly different to those of degenerate human IVDs.
The primary goal of HD is to restore the intracellular and extracellular fluid environment typical of normal kidney function [ 10].
Many of us expected inventory accumulation to top out in this environment of below normal expansion.
It could provide cultures with multi-mechanical stimulations and sufficiently mimic the complex mechanical environment of a normal articular cartilage.
Consequently, simulation of bionic mechanical environment of a normal articular cartilage is considered to be the optimal environment for culturing the functional articular cartilage in vitro.
The survival and differentiation characteristics of stem cells injected into NP explant cultures, under conditions modelling the environment of the normal IVD have been confirmed [ 32].
Although further investigation is required, we hypothesize that, with the possible exception of the stem cell compartment, CDX2 allows TCF7L2 to act as repressor in the Wnt-low environment of the normal epithelium.
Virtually all nuclear power plants worldwide release tritium into the environment as part of normal operations.
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