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In this paper, we offer a bias control technique involving the use of a second (reference) specimen for CWI analysis that is designed to compensate: (1) the thermally-induced velocity variation due to environmental temperature fluctuations; and (2) bias originating from experimental procedures.
We design and characterize devices that employ a thermoelectric module sandwiched between two heat exchangers with significantly different thermal masses and examine the effects of heat exchanger size and material selection, period of oscillation of the environmental temperature fluctuations, and radiative heat transfer on the thermoelectric power output.
Tan, et al. [53], decomposed the environmental temperature fluctuations into Fourier series form (shown in Figure 5).
Taking the environmental temperature fluctuations as input, based on the thermal error transfer function, the environmental temperature induced thermal error can be obtained.
In such circumstances, a stable baseline core body temperature may not be maintained when exposed to environmental temperature fluctuations [8], [47].
Convective PCR is extremely sensitive to environmental temperature fluctuations, and therefore is inherently unstable with limited applications.
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The other structure aims at keeping microcantilevers from the influence of environmental temperature fluctuation.
Therefore, environmental temperature fluctuation leads to the variation of growth rate [19].
Initially, a convective PCR device and related plastic capillary tubes were used to study the effect of environmental temperature fluctuation.
This implies that thermal baffle are able to significantly reduce the impact of the environmental temperature fluctuation and make the device suitable for PCR amplification.
Using this device we were able to minimize the impact of the environmental temperature fluctuation and carry out successfull PCR amplifications.
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