Sentence examples for environment progression from inspiring English sources

While it is now well established that the CSC component is the target to aim for treatment, it remains to be determined whether it is a unique target, and what is the best way to counteract its potential adaptation to the host environment: progression, expansion and response to treatment.

That is, without a permissive environment, tumor progression may not occur.

In the hyperlipidemic environment the progression of TA was highly exacerbated and the inflammatory CD11b+CD115+Ly-6Chi monocytes were preferentially recruited into the neointima.

This study tested the hypothesis that Brk is involved in regulating the tumour cell environment during progression and investigated the effects of suppressing Brk in breast carcinoma cells to determine in which contexts Brk may be a valid therapeutic target.

Changes in protein expression level determine developmental biology, response to stress or fluctuating environments, and progression of disease.

This process leads to a favorable immune environment for tumor progression.

Subcutaneous injection of asbestos-treated, but tumor-free mice with syngeneic mesothelioma tumor cells resulted in a significantly higher incidence of tumor growth when compared to naïve mice supporting the role of the environment in tumor progression.

The efficacy of early intervention is founded on the notion that changing the child's interactive experience with the environment alters developmental progression.

The switch from an M2 to an M1 promoting environment during atherosclerosis progression may impede apoptotic cell clearance as M2 cells have greater capacity for efferocytosis [90] (Figure 1); this is through various pathways such as the expression of MR [91] and up-regulation of MER proto-oncogene tryosine kinase (MERTK) (on M2c), which is not induced on M1 macrophages [49],[92].

Thus, Stat3 provides a link between oncogenesis and immunosuppression and plays a central role in the establishment of immunosuppressive environment and the progression of tumors [8].

Bacterial vaginosis is a heterogeneous syndrome characterized by diverse microbiota, some of which might be essential "founder" species necessary to establish an environment favorable to progression to BV.