Spectral variation, however, is still distinguishable among the three labeled sites and shows that R5 is reporting on the local environment of the RNA backbone.
In general, the side-chains of amino acids probe a different environment from that of the backbone, and charged side-chains probe a different environment from that of hydrophobic side-chains.
The stereochemical environment, the conformation of the backbone and side chains was analysed using PROCHECK [35].
Cut down either side of the backbone and discard the backbone.
Production of collagen, the backbone of skin, decreases.
In conclusion, while short term evolution of L. monocytogenes in natural environments involves limited diversification of the genomic backbone, phage-mediated genetic changes appear to be major mechanisms for diversification and evolution of L. monocytogenes during short evolutionary time frames.
Overall, our data indicate that short term evolution of L. monocytogenes in natural non-controlled environments involves limited diversification of the genomic backbone, but can involve considerable phage-mediated diversification as well as plasmid loss or gain.
Aloo, of course, means potato – the backbone of this dish.
As can be seen in Fig. 5a, under a more acidic environment, the protonation of phosphodieter backbone of DNA reduced the solubility of the DNA molecule, which eventually decreased the DNA hybridisation reaction rate.
Data centers, which are the backbone of corporate computing environments, now need far fewer physical machines.
