While burnout or stress-reactions are conceived of as reactions to a pressing environment, psychiatric disorders such as bipolar disorder, depression, anxiety are considered inherently multi-factorial, with e.g. hereditary contributions.
"They gave order to Tommy Johnson's life in an environment of disorder," said Maxine Schack, who represented the Neponsit Adult Day Health Care center, where Thomas Johnson Sr .was a driver and attendant.
A clinical geneticist (female, 40 years) put it as follows: "When I think of genetics I think of monogenetic disorders, but of course disorders (seen in primary care) are often complex disorders or multigene or gene environment interaction disorders.
In the absence of reliable visual information (e.g. extremely dark environment, visual disorders), the use of other information is vital.
Several studies have analyzed known polymorphisms in the DAT and the SERT genes as a function of specific environmental factors [113] proving that adverse environments entail disordered behavioral manifestations more often in the carriers of particular polymorphisms.
However, this mathematical result is not informative at the individual level - the only relevant scale from a preventive point of view – because correlation between abusive environment and conduct disorder may not be realized for a given child.
The combination of extremely high temperature and high hydrostatic pressure potentially also represent environment favoring intrinsic disorder.
