Sentence examples for envelope alterations from inspiring English sources

This suggests that cellular abnormalities 'downstream' of nuclear envelope alterations are commonly affected in diseases other than laminopathies.

Thus, in response to nuclear envelope alterations some important DNA damage sensors such as p53 or ATM were activated.

Well-defined abnormalities in HGPS cells include nuclear envelope alterations and reduced levels of the nuclear components, lamin B1, and LAP2α (Goldman et al., 2004; Shimi et al., 2011).

Finally, our results indicate that these findings can be extended to normal aging, suggesting that a common accumulation of genetic damage and nuclear envelope alterations with age could be responsible, at least in part, of the abnormal NF-κB activity reported in tissues from advanced aged donors.

Besides, these results also confirmed that the deficiency in TolC protein is not correlated with a bacterial envelope alteration inducing a general sensitivity of bacterial cells.

The HGPS-iPS cells that differentiated into vascular SMCs accumulated progerin and displayed the nuclear envelope alteration and premature senescence previously observed in HGPS fibroblasts (Cao et al., 2011; Capell and Collins, 2006).

Envelope Adjustment.

To do so, the RTQ-C was applied to two buildings in order to calculate the efficiency levels of their envelopes and possible alterations are proposed for upgrading the envelope performance where pertinent.

These pathological accumulations at the nuclear envelope cause severe alterations in nuclear morphology and organization, hampering the normal functions of cells and leading ultimately to premature aging phenotypes exhibited by affected patients [ 6].

Consistent with findings in mice, marked alterations in nuclear envelope morphology, abnormal localization of RanGAP1, and nuclear accumulation of mRNA were found in cortex of Huntington's disease patients.

The finding that roughly a fifth of nuclear envelope transmembrane proteins screened yielded alterations in flow cytometry cell cycle/DNA content profiles suggests a much greater influence of the nuclear envelope on the cell cycle than is widely held.