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However, the liver reveals 249 significant gene expression differences (p<0.05) showing significant down regulation of expression of several key genes affecting the entry of glucose into the cell and its metabolism via the glycolytic and tricarboxylic acid pathways.
The entry of glucose into cells is achieved via facilitated diffusion through the glucose transporters (GLUT) family [ 18].
The entry of glucose into the heart is mediated by members of the GLUT family of facilitative transporter proteins.
The process of entry of glucose across the cell membrane is controlled by hexokinases (HKs) and glucose transporters [ 19, 20].
Glut4 is a key protein in cellular entry of glucose and its translocation to the cell membrane is a well-known function of pAMPK [ 26].
It is generally accepted that chronic exposure to resistin adversely affects the entry of glucose into cells, thus counteracting the effect of insulin.
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For dicotyledons, there are four enzymatic steps that are essential in the formation of a starch polymer after the entry of glucose-6-phosphate via glucose-6-phosphate transporter (GPT) into the amyloplast [ 14].
However, as shown here, chemical inhibition of the entry of glucose-derived intermediates into the TCA cycle had no detectable effect on the development of asexual stages, possibly reflecting continued operation of glutaminolysis and catabolism of the carbon backbones of glutamate in this cycle.
Initial treatment with intravenous fluid and insulin allows sudden entry of plasma glucose and phosphate into the insulin-sensitive tissues for cellular phosphorylation, and plasma Pi may be drastically decreased.
Each molecule of insulin is required for the entry of one glucose molecule.
Considering that PDH is the primary entry point of glucose-derived pyruvate into the TCA cycle, we define (9) CMR Glc (ox ) (n ) = 1 2 ν PDH (n ), where the factor 1/2 is required as glycolysis produces two molecules of pyruvate for each glucose molecule.
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