r1 is the entry point of active work.
Consistent with this finding, it has been reported that an N-terminal His6 tag can promote PA-dependent entry of an active domain of the C2 toxin and epidermal cell differentiation inhibitor of Staphylococcus aureus.
Cholesterol binding to Scap prevents the protease-mediated release and nuclear entry of the active fragment of SREBPs, thereby blocking cholesterol synthesis and uptake from LDL (Horton et al., 2002).
The latter was shown to participate in the chlorite degradation mechanism and to adopt two distinct conformations, one pointing toward the heme iron (here referred to as "in") and one pointing toward the entry of the active site substrate access channel (here referred to as "out").
They found no association between CP and the risk of RRMS (OR: 0.8; 0.4 1.7) or PPMS (OR: 1.0; 0.3 3.7) when compared to healthy controls adjusting for latitude of residence at time of entry into active duty and education level [ 28].
[ 31] It is apparent in comparing student career choice at medical school entry with the current mix of active physicians that there is mismatch between student interest and the current physician workforce (See table 2).
Indeed, GROs are internalized rapidly by a passive process and accumulate in the nucleoli in contrast to the active entry of HB-19 and its accumulation in the cytoplasm.
Structures of p110α show a great deal of disorder or irregular structure in this region (Huang et al., 2007; Mandelker et al., 2009; Hon et al., 2012), and this may facilitate entry of water into the active site.
The G232 residue is located behind the Xe1 site, identified in Xe-pressurized crystallographic studies of Tt ba3, providing a small opening proposed to be the site of entry of ligands into the active site.
Active entry of Ca2+ through the oral epithelial layer is regulated by voltage-dependent calcium channels, such as demonstrated by the L-type alpha protein cloned from the reef-building coral Stylophora pistillata[ 147].
