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Taken together with repair propensities, our data suggest that the bending kinetics of MutS mismatched DNA complexes may control the entry into functional pathways for downstream signaling of repair.
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Entry Into The Museum Photo Creditt: Steven Rosenbaum).
Systems biology approaches are advantageous in providing predictive models of associations between epigenomic/genomic data and phenotypes offering an entry point for assays into functional relationships.
The tubuloglomerular feedback (TGF) mechanism regulates the rate of fluid and solute entry into the nephrons, the functional units of the kidney.
Altogether, our results indicate that CHIKV entry into HEK293T cells requires functional Eps15.
We conclude that a pulse of low level nuclear Prospero marks neuroblast entry into quiescence, suggesting a functional relationship.
According to the mapping of InterPro entries to GO [ 35], GO accession numbers were assigned to EST clusters, which were used to classify ESTs into functional groups by molecular function, cellular component, and biological process.
Thus, attempts to force these cells to divide bring about extensive DNA damage, which can determine different, non mutually exclusive end results: programmed cell death as a result of DDR activation, arrest in G2 phase if the corresponding checkpoint is functional, or entry into a catastrophic mitosis if it is not.
Our results showed that both the wild-type and mutant spike glycoproteins were functional and mediated virus entry into 16HBE cells (Figure 5A and 5B).
In S. cerivisiae, Ypt1 and the functional pair Ypt31/32 regulate entry into and exit from the Golgi, respectively [ 8, 9].
At the BBB, Bcrp forms a functional barrier against drug entry into the brain by pumping drugs out of brain capillary endothelial cells.
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