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Thus, STIM1 oligomerization is the critical transduction event through which Ca(2+) store depletion controls store-operated Ca(2+) entry, acting as a switch that triggers the self-organization and activation of STIM1-ORAI1 clusters at ER-PM junctions.
USP50 regulates HSP90-dependent Wee1 stability preventing mitotic entry, acting as another G2/M checkpoint [ 114].
We suggest, therefore, that Sig1R ligands are previously unrecognized inhibitors of TRPC5, TRPM3 and endogenous endothelial cell Ca2+ entry, acting independently of Sig1Rs.
Several experimental observations are consistent with the existence of a parallel NF-mediated signalling pathway that operates in root hair curling and bacterial entry acting in concert with the common symbiotic pathway [ 25, 68].
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He also told them his diary and the plans in it were "hypothetical, just thoughts and feelings", and that he showed it to a mental health worker, the entries acting as "basically a sort of therapy".
Second, differences in dispersion of repolarisation across the myocardium may result in a functional re-entry acting as a trigger for torsade de pointes.
Accordingly, it is debatable whether the observed differences in treatment effects between entry Hb subgroups is due to entry Hb acting as an effect modifier or is just a play of chance.
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Entry into acting was an unexpected move for Chou.
Such fluidity could stem from her original entry into acting as a way to control a stutter that developed when she was 6.
In T cells, mitochondria migrate instead to cell periphery following Ca2+ entry, thus acting as Ca2+ buffers and preventing SOCs inactivation [26].
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CEO of Professional Science Editing for Scientists @ prosciediting.com