The selection of two orthogonal columns for two-dimensional high performance liquid chromatography (LC×LC) separation of natural product extracts can be a labour intensive and time consuming process and in many cases is an entirely trial-and-error approach.
The subgroup of patients with MGMT promoter methylation status assessed was therefore not entirely representative of the whole trial population.
It is also questionable to exclude trials entirely from the review if they fall below a certain quality cut-point on a scale [ 24], whereas it can be entirely reasonable to include only trials that are adequately randomized and blinded, e.g. if the main outcome is subjective, such as pain.
Justice Rena K. Uviller of State Supreme Court in Manhattan denied the requests, which probably would have forced her to start an entirely new trial for one of the defendants.
But Ms. Keilen insisted that nothing short of an entirely new trial on the broader question of guilt or innocence would "repair the damage the affair has caused and restore integrity to the Texas criminal justice system".
He now faces an entirely new trial for bank fraud, without the benefit of a jury.
Or failing that, eBay wants the judge to order an entirely new trial.
And the adults were talking about an entirely separate trial involving an accused terrorist.
It was surprisingly hard to collect public data for this study as we required trials of at least 20 human subjects with a defined clinical binary outcome, i.e. (i) responders and non-responders, (ii) at least some detectable difference in gene expression at baseline between the two groups and (iii) the availability of a similar but entirely independent trial for testing purposes.
Our criteria for inclusion were (i) a dataset of at least 20 human subjects with a defined clinical binary outcome, i.e. responders and non-responders, (ii) at least some detectable difference in gene expression at baseline between the two groups and (iii) the availability of a similar but entirely independent trial for testing purposes.
Notably, the 2 contrasts are orthogonal, being computed from entirely different trials.
