A recent study, in which 66 G4C2 repeats were expressed in the central nervous system of mice, has shown that nuclear RNA foci, DPR inclusions and TDP-43 pathology were present in the cortex and hippocampus of mice, suggesting that the repeat itself, possibly through foci formation, RAN translation or another mechanisms entirely, caused aberrant TDP-43 deposition [ 23].
Yet at the same time cannibalism is viewed as completely taboo, aberrant in all circumstances.
More and more, she finds unsatisfactory an "untenanted life, with only an aberrant imagination for company".
The incident in Colmar on Saturday, however, was entirely down to the aberrant behaviour of one individual and is unlikely to produce the same soul-searching.
With just two exceptions (cases b and h in Figure 5), all molecules containing permutations (both correct and aberrant) lack IES sequences entirely, and furthermore contain only correctly excised (or correctly healed) junctions at all nonscrambled IESs.
An increasing amount of evidence suggests that aberrant driving behaviors are not entirely rational.
Not only are they unwelcome; they are aberrant.
However, it is not entirely clear how H2A.Z overexpression in cancer cells establishes aberrant chromatin states and promotes gene expression.
Moreover, this migration defect could also be induced between P8 and P14 by downregulating Dpy19l1, suggesting that aberrant neural migration upon Dpy19l1 knockdown cannot be entirely attributed to developmental delay (Fig. 7A-D; supplementary material Fig. S7).
The CpG island was entirely unmethylated in C8161 but densely methylated in C81 61, consistent with aberrant methylation underlying the absence of expression.
