We examined the use of rosiglitazone during its entire period of availability on the European market (2000 2010) and evaluated changes in the glycated haemoglobin (HbA1c) and fasting plasma glucose (FPG) levels among patients discontinuing this drug.
In contrast to our model, however, no constraint was placed on the number of doses available, resulting in drug availability throughout the entire course of the epidemic.
They're the studio that are often seen as the antidote to bland Hollywood commercialism, so Cars 2's vapidity stuck in the craw of critics almost as much as the sudden availability of entire fleets of branded merchandise.
Several recent great megathrust earthquakes have ruptured across entire seismogenic widths, and availability of extensive seismic data has enabled the first detection of frequency-dependent radiation as a function of depth on the fault during the ruptures (e.g., Lay et al., 2012).
Furthermore, it has been reported that the availability of entire genomes may not be clinically informative (Roberts et al. 2012).
16 We identified patients in each database with a prescription for any OHA between 1 January 2000 and 31 December 2010, encompassing the entire period of rosiglitazone availability in Europe.
We examined the use of rosiglitazone-containing products over the entire period of their availability in Europe (2000 2010) using routinely collected data in medical databases in Denmark and in the UK.
More recently, with the availability of entire genome sequences for rice and Arabidopsis, many Mu-like elements associated with fragments of host cellular genes have been found in those two plant species [ 17, 18, 4].
The study of entire genomes increases the availability of information on neutral loci, and thereby the accuracy of estimates of demographically important parameters, such as the inbreeding coefficient (F) [ 19, 20].
The availability of entire genome sequences for an increasing number of species including P. infestans, P. ramorum and P. sojae have proved novel opportunities to identify and evaluate potential SSR markers identified by computational tools (Abajian, 1994, ) [ 27, 28].
With the availability of entire genome sequences, much progress has been made towards the understanding of gene duplication dynamics [ 2, 3] and the evolutionary forces responsible for the retention of a proportion of duplicate genes, such as neo-functionalization [ 4] and sub-functionalization [ 5], both at the level of gene expression patterns [ 6, 7] and protein sequence evolution [ 8].
