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If cells that have gone through abnormal mitosis enter the next cell cycle, they often activate the p53 dependent apoptosis pathway (Thompson and Compton, 2010).
We show data utilizing immunocytochemistry, flow cytometry and microarray technology to prove that mitotic cells selected by mitotic shake-off enter the next cell cycle normally, without activating stress response genes.
When the shift occured more than 9 (resp. 15) minutes prior to division, 50% (resp. 100%) of the cells arrested (Fig. 2g), implying that they did not have enough Cln2 to enter the next cell cycle.
Unrepaired CNDAC-induced SSBs are converted to one-ended DSBs when cells enter the next cell cycle.
Perhaps some cells within an anther have higher residual TAM activity than others and are thus able to enter the next cell cycle earlier than other cells.
In fact, the fate of individual cells seems stochastic; cells may die from mitosis or undergo mitotic slippage followed by cell cycle arrest or apoptosis, and some even survive and enter the next cell cycle (Shi et al, 2008; Gascoigne and Taylor, 2008).
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The message HANDOVER COMPLETE is the indicator that the train has entered the next cell and left the current one.
The subsequent mitosis in His C mutants is completed and cells enter into the next cell cycle.
It has been shown that hESC cells are already pre-committed in mitosis to enter the next S phase in the absence of external stimuli [36].
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