enter clinical development

USAGE SUMMARY

The phrase "enter clinical development" is correct and usable in written English.
It can be used when discussing the process of advancing a drug or treatment into the clinical trial phase of research and development. Example: "After successful preclinical trials, the new medication is set to enter clinical development next month."

✓ Grammatically correct

Science

News & Media

Academia

Human-verified examples from authoritative sources

Exact Expressions

10 human-written examples

CT-322, the first engineered FN3 to enter clinical development, is now entering Phase II trials for glioblastoma multiforme.

Drug Discovery Today

Over 60 peptide drugs are approved in the United States and other major markets, and peptides continue to enter clinical development at a steady pace.

Bioorganic & Medicinal Chemistry

The first of these compounds to enter clinical development were BMS-354825 (BristolMyersSquibb) and AMN107 (Novartis Pharma) and, from Phase I results, both of these promise a breakthrough in the treatment of imatinib-resistant CML.

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Certain drugs are currently in phase I III clinical trials as single agent or as a combination partner for the treatment of various tumour types, and many compounds are in late preclinical development and might enter clinical development soon.

Progress in Medicinal Chemistry

"We are able to make new protein constructs based on evolving scientific principles," he says, "and then screen for candidates that can enter clinical development.

Science Magazine

"I hope that teixobactin will now enter clinical development as the basis for a new drug to treat infections". There is wide concern that the world is cruising into a "post-antibiotic" era.

BBC

Human-verified similar examples from authoritative sources

Similar Expressions

50 human-written examples

Over the last several years, a new generation of drugs directed at epigenetic modulators have entered clinical development, and results from these trials are now being disclosed.

Nature

Preclinically, various simple in vitro approaches and animal models are used to identify cardiac liabilities before a compound enters clinical development.

Nature

New polymer therapeutic concepts continue to emerge with a growing number of conjugates entering clinical development, for example PEGylated-aptamers and a polymer-based siRNA delivery system.

Current Opinion in Biotechnology

A number of orally available nonpeptidergic small molecules capable to pass the blood-brain barrier have been discovered; only some of these compounds entered clinical development.

European Journal of Pharmacology

About half of the recently approved antimicrobial agents for gram-negative pathogens, those pending approval, and those entering clinical development are β-lactam-β-lactamase inhibitor combinations.

Current Opinion in Pharmacology

Expert writing Tips

Best practice

Avoid using the phrase in contexts unrelated to drug or therapy development, as it is a specific term with a defined meaning in this field.

Common error

Avoid using "enter clinical development" loosely to mean simply "begin testing". The phrase specifically refers to the formal process of moving a treatment into the clinical trial phases of research and development. Use less specialized language if you're referring to preliminary or exploratory testing.

Linguistic Context

The phrase "enter clinical development" functions as a verb phrase indicating the initiation of a process. It describes the action of a drug or therapy progressing into the clinical trial phase. Ludwig AI confirms its usability in written English.

Expression frequency: Common

Frequent in

Science

79%

News & Media

13%

Academia

8%

Less common in

Formal & Business

0%

Encyclopedias

0%

Wiki

0%

Ludwig's WRAP-UP

In summary, the phrase "enter clinical development" is a grammatically correct and commonly used term, primarily within scientific and medical contexts, to describe the transition of a drug or therapy from preclinical studies to human clinical trials. Ludwig AI confirms that this expression is appropriate in written English. When writing about this topic, it's important to understand its specific meaning and avoid using it loosely. Alternative phrases, such as "begin clinical development" or "start clinical trials", may be used depending on the desired nuance.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

begin clinical development

Replaces "enter" with "begin", emphasizing the start of the clinical development phase.

commence clinical development

Uses "commence" instead of "enter", suggesting a more formal initiation of clinical development.

initiate clinical development

Similar to "commence", "initiate" highlights the act of starting the clinical development process.

advance to clinical development

Focuses on the progression of a drug or treatment into the clinical phase.

proceed to clinical development

Indicates the next step in a drug's journey is clinical development.

undergo clinical development

Shifts the focus to the drug being tested and its experience during clinical development.

start clinical trials

Emphasizes the start of clinical trials, a key component of clinical development.

move into clinical trials

Similar to "advance to clinical development", highlights the progression into clinical trials.

be put into clinical development

Passively emphasizes the action of a drug being placed into the clinical development phase.

transition to clinical development

Highlights the change of phase from preclinical to clinical.

FAQs

What does "enter clinical development" mean?

The phrase "enter clinical development" refers to the stage when a drug or therapy begins human trials after successful preclinical studies, marking a significant step in its research and development process.

What is the difference between preclinical and clinical development?

Preclinical development involves laboratory and animal testing to assess safety and efficacy, while clinical development involves human trials to further evaluate safety, efficacy, and optimal dosage.

What can I say instead of "enter clinical development"?

Alternatives include "begin clinical development", "start clinical trials", or "advance to clinical development", depending on the specific nuance you want to convey.

Why is it important for a drug to "enter clinical development"?

Entering clinical development is a critical milestone because it signifies the potential for a new treatment to be tested in humans, potentially leading to regulatory approval and availability to patients in need.