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Investigating the governing dynamics that regulate such systems entails experimentation of the trial-and-error flavour, but the, sometimes, colossal gaps between system outputs under slightly varying initial conditions have done little to decrypt the black-box-like modus-operandi of such systems.
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When Kilgore started out at the Journal, reporters sometimes sold advertising, and Kilgore's own early work as a reporter entailed experimentation with forms carried over from the nineteenth century, such as articles written as letters to an imaginary friend.
We recognize this would likely entail additional experimentation and analysis.
Creativity in any field requires experimentation, and experimentation necessarily entails mistakes.
Science, any system of knowledge that is concerned with the physical world and its phenomena and that entails unbiased observations and systematic experimentation.
Finally, animal experimentation, pre-clinical toxicity testing, and clinical development entails large resources and an organization to meet regulatory requirements, and is today probably best led by large pharma.
It also entails gathering key knowledge regarding the host architecture and translocation machinery and associated substrate recognition via experimentation and integration of diverse computational analyses from many proteins and, where possible, that are derived from different species within the same genus.
(Whatever that entails).
Democracy entails risks.
Which entails some risk.
Sovereignty entails obligations.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com