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Frailty is a state of increased vulnerability that entails a high risk of adverse outcomes.
Using solely clinical criteria entails a high risk of dispensing unnecessary antimicrobial treatment with the risk of emergence of multidrug-resistant organisms [ 5].
Members of Jehovah's Witnesses who refuse blood transfusion create a dilemma if the operation entails a high risk of life-threatening blood loss.
Few professionals mentioned that they believed consanguinity entails a high risk and some felt the increase in risk was a subject of some debate among experts, and that there were no exact facts to communicate to clients.
Regarding PGD, in Section 2 of Chapter 4 it is stated: "Pre-implantation genetic diagnosis may only be used if the man or woman has a predisposition towards a serious monogenetic or chromosomal hereditary disease, which entails a high risk of having a child with a genetic disease or impairment.
It remains to be investigated whether this female adaptive behaviour (i.e., attacking males only after ensuring sperm) has evolved from selection imposed by males that preferentially approach non-aggressive females or because high male mortality during the mating season [28], [43], [47] entails a high risk of remaining unmated for females in natural populations.
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Early menopause onset entails a higher risk of cardiovascular diseases, osteoporosis and higher mortality.
The link between obesity and OA is well-established and particularly supported by longitudinal data showing that obesity entails a higher risk for developing severe OA (6).
On the other hand, axonal injury often recovers incompletely, and slowly, over months or even years, and entails a higher risk of pain developement [ 29].
Open repair was considered, but owing to the presence of multiple comorbidities and an extremely dilated aorta in the landing zone (45 mm) which made thoracic endovascular aortic repair infeasible, it appeared to entail a high risk for perioperative morbidity and mortality.
Industries entailing a high risk included salt mining, manufacture of carpets, paints, plastics and industrial chemicals.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com