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All those events entail substantial changes and balance between many processes such as the cell cycle, cellular growth, proliferation, differentiation, angiogenesis, steroidogenesis and atresia to determine the ultimate fate of follicles.
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We test these implications in a large panel of Spanish manufacturing firms from 1991 to 2005, looking at the effects of three labour market reforms which entailed substantial changes in the firing-costs gap.
Recovery among Sahrawi refugees has thus entailed very substantial changes in environmental, technical and social relations of production and exchange compared with the nomadic past, and in several ways reflects refugees' dependence on, and engagement with, a transnational political economy.
There are numerous options, most of which would entail a substantial change in working practices.
These are all substantial changes.
"These are substantial changes.
Thereafter there were no substantial changes.
Both moves typically entail substantial new R&D and marketing capabilities and are fraught with risks.
The analysts added that the potential deal would likely entail "substantial" cost savings over three years.
Like substantial changes to monsoons, for one.
This may require substantial changes in personnel.
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