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The spread of Isis into south Asia has major ramifications.
This observation may have major ramifications for arsenic-containing groundwater percolating through iron-rich soil.
Such a decision, however, would have major ramifications for the debate over faith-based initiatives.
The Trident vote will also have major ramifications for the Labour party.
Clarkson's departure could have major ramifications for BBC Worldwide's global TV deals.
CEN says the article has had major ramifications for its business.
His update did enable Heartbeat, but an "oversight" led to an error with major ramifications.
These questions have major ramifications for the care of patients with ICH or IVH.
This is a career-shaping choice with potentially major ramifications and he must make it for himself.
As the rate-manipulation scandal spreads to other banks, the fallout could have major ramifications for the financial industry.
Before committing to doing the article I told her that, based on my experience, there could be major ramifications.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com