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RCTs are believed to currently provide the best level of evidence that ensures efficacy of drugs interventions or strategies.
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Over the past few decades, tendency toward innovative drug delivery systems has majorly increased attempts to ensure efficacy, safety and patient acceptability.
Disinfectants with claimed activity against Clostridium difficile must be evaluated to ensure efficacy against the spores that comprise an environmental source of patient infection.
Demand for CI models to be transparent is to ensure efficacy and safety of a drug by fulfilling modern requirements for ultimate control and understanding of every element of the process including modeling procedures.
Troughs of between 5-10 µg/ml are thought to be necessary to ensure efficacy [ 2].
Further successful treatment of medulloblastoma may rely on proper management of the NFκB pathway to ensure efficacy of current therapies.
So, to ensure efficacy of adherence interventions a tailored approach towards patient-specific adherence barriers is needed.
There are policy responses available within each of these domains to ensure efficacy, minimising risks and optimising cost effectiveness.
The consensus was that the amoxicillin PEP dose should err on the higher end in favor of ensuring efficacy.
Indeed, linezolid serum concentrations during infection should reach sufficient levels for most causative pathogens to ensure efficacy.
In the case of the HAM-D and the MADRS, such reliability is particularly important for ensuring efficacy of clinical drug trials.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com