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The enrolments were made during 3 7 days of life, and therefore the role of probiotics on early onset sepsis could not be evaluated.
The enrolments were made during 3 7 day of life, so we cannot comment on the role of probiotics on early onset sepsis.
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Firstly, in an attempt to improve the feasibility of data collection and the geographic distribution of patient enrolment, decisions were made regarding the need for a limited set of core clinical variables.
Upon enrolment, systematic recordings were made of the patients' demographic characteristics and medical history using standardised written questionnaires.
Physical and physiological assessments were made at enrolment and then at the 7th, 13th and 20-26th weeks. 20-26th weeks
All clinical decisions, for example to thrombolyze the patient if indicated, were made prior to enrolment in order not to introduce any delay to best clinical care.
Upon enrolment in both seasons, systematic recordings were made of the patients' demographic characteristics and medical history using standardised written questionnaires [ 21, 22].
We define prospective in the sense that data definitions were made in agreement with the rationale of the study prior to the enrolment period, and that measurements are made in agreement with these definitions [ 13].
Efforts were made to contact the children and adolescents who were absent in the class, for enrolment to the study.
In many cases, progress in enrolment has been made at the expense of education quality, while other education targets have been neglected, such as early childhood care and education, literacy, youth and adult education and life-skills.
No official diagnosis by a medical professional was made at enrolment, rather, parents were counselled about the results of the GMs meaning their baby was at very high risk for CP.
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