BRCA1/2mut status was obtained as part of the clinical trial enrolment, and sources included the patient's genetic test results, and in one case, deleterious mutation risk outcome estimates using the BRCAPro model (BayesMendel Lab, http://bcb.dfci.harvard.edu/bayesmendel/brcapro.php).edu/bayesmendel/brcapro.php
This chapter explores the key methodological elements of these registries in terms of patient enrolment, the source of exposure and outcome information, outcome definition and ascertainment and comparator groups and how these elements may influence the reported risk estimates.
To the extent that age of enrolment is a source of variability in impact sizes, our estimates of impact size may therefore have larger standard errors than the Abecedarian study.
As each source of patients was mainly constituted by a specific target of MS disease stage, multiple sources of enrolment were necessary.
According to Kumar, in India, admission to medical school is so profitable that the transactions are patronised by politicians who take the enrolment payments as a source of income [ 20].
We estimated the likelihood of exposure to elevated nitrate from drinking water (⩾10 mg nitrate per litre) based on the census tract location of a participant's residence at enrolment, as the usual source of drinking water was not ascertained for the cohort.
The General Registry Office of Forlì was the data source for the enrolment of the cohort.
Every one or two weeks we approached the source population, until enrolment of a sufficient number of patients from a particular GP was realised.
This pilot will be used to identify problems with the research design/processes; refine data collection and analysis; assess adequacy of data sources; examine selection and enrolment processes; and assess the participants' perspective on participating.
This is the only source of information on enrolment rates for children between 5 and 6 years According to this report, the enrolment rates for 5- to 6-year-olds in 2005 06 was 27.27% (79,454 children including 39,884 girls), which represents an increase from 24.56% in 2004 05.
