To exclude potentially developing cases before or near the period of enrolment, we restricted our analysis to individuals who were diagnosed after 2 years of enrolment.
Even though the unit of enrolment was restricted to a household to limit adverse selection, this rule was not strictly followed.
For the CBHI scheme in Nouna, even though enrolment was restricted to a household, this rule was not strictly enforced and we found that there were partially enrolled households.
The parameters of the Cox models were estimated by pooled logistic regression models, modelling the change in baseline hazard since enrolment using a restricted cubic spline with knots at the 10th, 50th and 90th percentiles (Weeks 8, 28 and 48).
Starting in 1992, enrolment was initially restricted to patients with operable LC; however, case definition was expanded in August 1996 to include inoperable LC to reflect the full spectrum of LC patients.
This study restricted enrolment to the tumour necrosis factor α inhibitor/biologically naïve population on background MTX, thus limiting the ability to extrapolate efficacy and safety to biologically experienced subjects or to assess the safety of baricitinib with other background DMARDs commonly combined in RA treatment.
About 30% of acute stroke occurs in people aged over 80. 6 7 8 The NINDS National Institute of Neurological Disorders and Strokee) trial initially restricted enrolment to patients aged up to 80. 9 The age criterion was lifted after they enrolled 188 patients in part A of the trial, but they enrolled only 42 very elderly patients.
Thirty eight of the studies (31.1%) restricted their enrolment to a specific subset of women (preterm labor, PROM, PPROM, prolonged rupture), while a majority of studies (n = 80, 65.6%) examined all pregnant women.
Even auto-enrolment – the new system that requires employers to provide employees with access to a workplace pension scheme and to contribute to that scheme – will exclude a disproportionately larger percentage of women than men because the employer's duty to auto-enrol employees is restricted to employees with a specified minimum income.
There was no restriction for age, gender, or disease stage at enrolment, but the study was restricted to patients with the NSCLC type of lung cancer.
