If an individual goes against the default when it is an automatic enrolment (plan A), they opt-out of the program.
Conversely, if the individual decides against the default when it is an optional enrolment (plan B), they opt-in to the program.
The enrolment is planned over a period of 24 months, which corresponds to a total study duration of 36 months.
Based on this, the sample size was calculated to approximately 34 subjects at a presumed agreement of 90% (CI 20%; chance agreement: 50%) [ 24] and enrolment was planned to meet this criterion.
Completion of enrolments is planned for the middle of 2012.
The Medicare Supplement includes inpatient and outpatient Medicare supplemental medical claims, linked to drug, person-level enrolment, and benefit plan design data for retirees covered by their previous employers.
There is also huge variation in enrolment in private plans, compared with Medicaid, the health programme for the poor.
Additional data elements include patient demographics, health plan type, payer type, provider specialty, and health plan enrolment dates.
Planned enrolment was 240 patients, but the trial was stopped early following a planned interim analysis after the accrual of 152 patients, and analysis of response rates and survival for the first 120 patients entered in the trial.
27 Planned enrolment was undertaken to meet these criteria.
