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During the study's enrolment phase, the aim was to enroll the oldest children first.
The enrolment phase of the Moli-sani study was supported by research grants from Pfizer Foundation (Rome, Italy), the Italian Ministry of University and Research (MIUR, Rome, Italy)—Programma Triennale di Ricerca, Decreto no.1588 and Instrumentation Laboratory, Milan, Italy.
After the enrolment phase, the created GMM models were tested.
In the final application we might then use a relatively short enrolment phase and do acoustic model retraining (and/or online speaker adaptation), to obtain better recognition results.
Such retraining of the acoustic models is also possible in a realistic CALL application, albeit not online, after a so-called enrolment phase, as used in dictation systems.
Usually in biometric system the enrolment phase is conducted in a controlled way where the image quality, finger positioning, and so forth.
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The enrolment of patients began in December 2009 and both enrolment phases will end before the end of 2011.
Details of the case and control enrolment in the New England Case Control (NECC) study were previously described (Terry et al, 2005; Harris et al, 2011); in brief, cases and controls from the NECC study of ovarian cancer come from three enrolment phases (1992 1997, 1998 2002 and 2003 2008) corresponding to three funding periods.
To evaluate the effect of the treatment with imatinib mesylate on SSc-ILD, the study was structured according to Simon's optimal two-stage design [ 16], a strategy devised for phase II studies to limit the number of subjects who will undergo inefficacious therapy, consisting of two subsequent enrolment phases [ 16, 17].
At present, additional studies are being conducted with various other non-antigen-specific immunosuppressive/immunomodulatory agents and are in different enrolment phases [e.g. mycophenolate mofetil ± anti-IL-2 receptor monoclonal antibodies (daclizumab), anti-CD20 monoclonal antibodies, thymoglobulin, IL-2 + sirolimus, CTLA4-Ig, IL-1-receptor antagonist][ 28].
See patient flow diagram for recruitment and pre-enrolment phase details.
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