Each patient will have all four criteria assessed at baseline using either recent tests or post-enrolment evaluations.
CPG was the study physician responsible for enrolment and evaluation of study subjects.
At times the stage of the trial (enrolment or evaluation etc) associated with the population number is not specified.
AP was the study coordinator responsible for enrolment, clinical evaluation and saliva sampling of the study subjects and participated in the planning of study design together with the FinOM Study Group.
Five studies presented outcome data from all enrolled dogs in the treatment group to which they were originally allocated and there were no losses between enrolment and evaluation [ 13, 16, 22, 24, 35].
All adults who were admitted to our intensive care unit (which cares for both medical and surgical patients) during a period of 15 months (June 2008 to September 2009) were eligible for enrolment and retrospective evaluation.
A sample size of 300 subjects was planned for enrolment for descriptive evaluation of safety of the vaccine.
All patients were examined clinically before enrolment by laboratory evaluation, which included a complete blood cell count and electrolytes, blood urea nitrogen, creatinine, calcium, phosphorous, bilirubin, alkaline phosphatase, aspartate aminotransferase, alanine aminotransferase, total proteins and albumin.
MS was responsible for data collection, patient enrolment, clinical and radiographical evaluations, manuscript writing, and final approval of the manuscript.
Participants underwent clinical evaluation at enrolment and at each visit.
Figure 1 illustrates the flow diagram of patient evaluation and enrolment.
