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Patients had to have active disease at time of enrolment, defined by the presence of at least 2 tender and 2 swollen joints out of the 68 joints for tenderness and 66 joints for swelling assessed.
Exclusion criteria were infants having a congenital disease, a serious infection at birth or an inability to feed (initially assessed by the lack of a suck reflex), mothers who were seriously ill at the time of enrolment (defined as bed bound for more than 24 hs), mother participating in other studies and/or mothers who were known to be HIV infected.
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Enrolment is defined as the first stage in nurse production.To assess pre-service attrition between training enrolment and registration with the NCK, data for a cohort that enrolled in training from 1999 to 2004 was analyzed.
Cancers detected less than 100 days after enrolment were defined as being detected at the entry screen.
Treated diabetes at enrolment was defined as yes or no if the participant reported ever having been treated or not for diabetes with pills or insulin shots.
Once two PD diagnoses had been established for each patient, the most recent 12 months of continuous enrolment was defined as the follow-up period, and the first date of this period was classed as the index date (Fig. 1).
A total of 31 patients (75.6%) had radiological evidence of disease progression at the time of enrolment as defined by comparison of baseline imaging studies, with imaging studies obtained within the previous 6 months; 34 (82.9%) patients had received therapy before enrolment, five (14.6%) of them systemic chemotherapy or sorafenib (Table 1).
Prevalence of diabetes at enrolment was defined by a positive answer to the question: 'did a doctor ever say that you had sugar diabetes or high blood sugar when you were not pregnant', or by reported use of medication to treat diabetes collected on the study medication inventory.
Enrolment Actors define and detail acceptance by developing a specific role in the network.
Each community project sought to enrol all consenting community members during defined enrolment periods.
This may have been because the criteria for enrolment were loosely defined as 'more than expected blood loss', resulting in the enrolment of women with less severe blood loss than anticipated.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com