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The timing of enrollment onto the waitlist is important as this is a proxy measure for the concordance of preferences for surgery between a patient and surgeon.
Patients with advanced cancer at the time of enrollment onto investigational therapy should have made an explicit transition to palliative care goals but often have not.
Such trials are being pursued within the National Clinical Trials Network (NCTN), which possesses unique qualifications to perform widespread molecular screening of tumors for patient enrollment onto therapeutic clinical trials.
In addition, no prior chemotherapy within 5 years of enrollment onto this trial was allowed or radiation to the tumour.
The measure was defined as "Enrollment onto study, quality mRNA obtained, gene chip completed, tumor board held, medical monitor review and approval, start of treatment by 21 days post biopsy/surgical resection date, and completion of 1 cycle of therapy".
CRAs reported that enrollment onto CCL studies may be enhanced where other competing studies can be minimized, such as after the initial period of diagnosis and when there are fewer disease-specific therapeutic studies available.
Similar(49)
Estimates of ART enrollment in low- and middle-income countries suggest that at the end of 2008, 45% of women and 37% of men who qualify for treatment were enrolled onto an HIV care and treatment programme [ 10].
Archival tumor specimens were sampled prior to enrollment of patients onto study.
A study of the Southwest Oncology Group SWOGG) compared the enrollment of older Americans onto SWOG trials from 1993 to 1996 to the actual proportion of older persons with cancer.
At enrollment, a detailed history and examination was recorded onto standardized proformas.
For each method, we recorded the total time required for enrollment, and the time required for manual transcription (paper) onto a computer database.
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