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The success of immunization registries is dependent on broad participation of immunization providers and comprehensive enrollment of persons vaccinated.
This could have introduced a selection bias favoring enrollment of persons with less opportunity for direct contact with the index patient.
During the course of recruitment, the investigators agreed to modify the glycemic inclusion criteria to allow enrollment of persons with fasting glucose of 90 125 mg/dl as long as the 2-hour plasma glucose concentration was 170 199 mg/dl, in recognition of the high risk of diabetes in such persons.
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The selection bias inherent in the enrollment of healthy persons in our study, as well as in those enrolled by Wolfe et al. (11 ) and Switzer et al. (10 ), greatly limits the ability to identify any potential acute or severe associated diseases.
Enrollment of test persons was performed from 15 May 2005 until 27 January 2006 in the Department of Cardiology and Pneumology, University Medical Center Göttingen, Germany.
We selected extra buildings to ensure enrollment of one person per building.
Selection of extra buildings (25%) ensured an a priori restriction of enrollment of one person per building with a sample size goal of 400.
Finally, in response to being asked regarding enrollment of children, one person said: "There has to be mutual benefit," while another respondent said "If I feel that the study will be of benefit".
When considering the distribution of time-weighted arsenic concentrations since 1971 according to area of enrollment, concentrations among persons enrolled in Aarhus were higher, with a median of 2.11 μg/L compared with 0.58 μg/L in Copenhagen.
We anticipated that enrollment of 30 HIV-positive persons would enable us to enroll at least 10 serodiscordant couples, including HIV-positive men and negative pregnant women.
It targeted the enrollment of 80 community-dwelling persons, aged 70-85 years, who were at risk for cognitive decline but who did not have mild cognitive impairment [ 17] as defined by the inclusion/exclusion criteria related to cognition (Table 1).
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