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Second, our study participants might not represent the general MSM population in the two sites due to the potential limitation of enrollment methods.
Detailed study eligibility criteria and enrollment methods have been described elsewhere [ 27, 39].
From the initial establishment period, PSU had two kinds of enrollment methods.
Details regarding the recruitment and enrollment methods have been documented previously (Freeman et al. 2008; Locke et al. 2010).
This difference could be attributed to differences inherent to slum communities and to difference in enrollment methods as the Riedemann's study used dogs brought into veterinary clinics, while this study enrolled dogs directly from households in the communities.
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Recruitment followed an open enrollment method from January 15 , 2008to September 1 , 2010
The arrival-stratified models likewise controlled for sex, age, NYC residence, and smoking status, as well as work days in the time period and total duration of work, exposure to the dust cloud, organization, work on the pile, and enrollment method.
Additional details of case and control enrollment, laboratory methods, and statistical analysis are provided in the Supplementary Data.
From 2004 2005 through 2012 2013, observational studies of influenza VE were conducted in a defined community cohort using consistent enrollment and laboratory methods [ 7, 13– 17].
With the exception of the definition of the index date and the precise time period for continuous enrollment, the study methods and variable definitions mirror those of our previously published study [ 18].
HLA-A02 and HLA-A03 supertypes were fairly evenly distributed among vaccinees meeting enrollment targets (see Methods) comprising, respectively, 5 and 3 volunteers in the first cohort, 3 and 6 volunteers in the second cohort, 3 and 4 volunteers in the third cohort, and 4 and 7 in the fourth cohort.
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