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In Belarus, Latvia, Moldova, and Romania, additional enrollment was stopped when a preagreed number of patients were enrolled to avoid overrepresentation of patients from these countries in the cohort.
No female subjects were enrolled to avoid potential risks of adverse effects on the fetus during early pregnancy.
Colistin is an antibiotic with a well-documented tubular toxicity [ 45]; domiciliary patients were enrolled, to avoid selection bias between septic and toxicity groups.
In fact, with the exception (in this study) of a small minority of non-nulliparous women who had never breastfed, only nulliparous women were enrolled, to avoid the confounding factor of breast-feeding, known to determine a significant decrease in organochlorine body burden.
Calves younger than 22 days of age were not enrolled to avoid potential false positive results during viral diagnostic tests (i.e., real time quantitative PCR, qPCR) due to the modified-live vaccines administered at 1 and 8 days of age [ 64].
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To mitigate sample size limitation, patients were enrolled consecutively to avoid selection bias.
Thirty-two patients were enrolled to the study.
Of the 101,045 enrolled pregnancies we included only singletons and first enrolled pregnancies to avoid dependencies among correlated measures (n = 87,056).
Second, only male subjects were enrolled in the study, to avoid confounding effects of the female menstrual cycle.
Enrolled participants were required to avoid prolonged exposure to sun or UV light and to discontinue nonmedicated emollients and medicated psoriasis shampoos 24 hours before each study visit.
But the reps were told to avoid enrolling pregnant women.
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