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The enrolled subjects underwent follow-up examinations at baseline and after 9 months of enrolment.

Pneumonia was diagnosed in 24%% of enrolled subjects.

HRQL was measured using the Short Form 36 Health Survey (SF-36) in all enrolled subjects.

None of the enrolled subjects had sleep deprivation or alcohol ingestion the day preceding the recordings.

Among enrolled subjects, 84% had migraine, 13% had episodic TTH, and 3% could not be classified.

EAEC was sought in stool samples in enrolled subjects by HEp-2 cell assay.

Of 172 enrolled subjects, 38 were excluded for incomplete data or multiple entries, leaving 134 study patients.

All enrolled subjects were Caucasian.

Clinical characteristics of enrolled subjects are presented in Table 1.

Over two thirds, (68%) of all enrolled subjects were females.

All enrolled subjects were unrelated ethnic Han Chinese.

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