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Pivotal trials for ophthalmic devices enrolled significantly fewer patients on average than pivotal trials for ophthalmic drugs (median 324 vs 809; p=0.005; total 9022 patients).
However, the Rochester site enrolled significantly more white non-Hispanic children in the study than the Nashville site (risk ratio [RR] = 1.3, p = 0.0002), representing differences in overall racial distribution between the sites.
For trials performed exclusively within one of the five major geographic groups, those performed outside high-income regions enrolled significantly more participants than trials in the high-income group.
Women from China were enrolled significantly later in their pregnancies than women in the U.S. (p =.04, mean difference of 1.52 weeks), yet the average difference in gestational age across the matched sets was 2.66 weeks.
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The average gestational age was 27 weeks at study enrollment (range: 13-39 withs), witHIV-positiveve women enrolling significantly earlier in pregnancy.
These paperless systems have the potential to enroll significantly more people.
Ironically, some private universities like mine, Trinity, now enroll significantly more low income students than many state universities -- we figure out how to make college affordable, but we cannot possibly fill the gap left by the rapidly-declining number of affordable seats in public schools.
Compared to historical control data, Cmin in the women enrolled was significantly higher whereas Cmax was significantly lower.
People who did not qualify for a subsidy enrolled in significantly higher numbers than those who did.
The present study found no significant statistical differences between healthy control males and females, although all enrolled participants significantly differed.
In a previous analysis focused on women in the US sites of the PACTG 316 trial, black women (accounting for nearly two-thirds of the women enrolled) were significantly less likely to achieve undetectable viral loads by delivery than white women [ 35].
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