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Included were (1) scans from mice studied at baseline prior to any treatment and (2) any subsequent scans from mice enrolled in control groups not receiving any drug substance.
Despite the fact the regulatory agencies recommend that placebo should not be continued for more that 3 6 months in RA trials [ 101], Estellat and Ravaud [ 102], through a revision of all RCTs of biological DMARDs ended after 2002, highlighted that 6,518 RA patients enrolled in control arms were continuing their previously ineffective treatment for more than 6 months.
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Approximately 2.0% of placebo patients enrolled in controlled trials experienced a serious bleeding event over the 28-day period.
All control patients enrolled in the control group were requested to have a Mini Mental State Examination (MMSE) score of 28 or higher.
In a study with hospital controls, study results can be biased if the exposure under study is associated with conditions enrolled in the control series (Miettinen 1985).
Women with breast cancer enrolled in the control group (Non-MBSR) were assessed at similar times.
Between June 1st and August 17th 2012, 467 divers were enrolled in the control group of the parent study.
Sixty-four patients with comparable distribution of hematological disorders, but who did not develop IA, were enrolled in the control group.
Sixty-two individuals were enrolled in the control group.
The same number of healthy people was enrolled in the control group.
Of the 2019 women enrolled in the control arm, 1908 (94.5%) were cytology negative.
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