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Many clinical studies have enrolled highly heterogeneous patient populations in terms of age, comorbidities and, importantly, disease severity [ 12].
18– 20 However, these trials enrolled highly selected patients who were middle-aged, prevalently male, and with reduced systolic function.
However, all included trials enrolled highly selected samples of people requiring anticoagulation therapy, and so it was uncertain whether there was strong external validity.
Most of the studies evaluating the efficacy of adjuvant chemotherapy in non-small cell lung cancer enrolled highly selected participants with good functional status and a low number of comorbidities; thus including a limited number of older participants.
7 32 33 Importantly, these analyses included studies of relatively short duration and that enrolled highly selected patients.
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Paclitaxel-eluting stents (PES) have been proved effective in randomized trials enrolling highly selected patients.
These new schools would recruit and enroll highly qualified Black and Latino students who would attend classes with the other students in the building and receive extra support when needed.
Black and Latino students are more likely than white students to be enrolled in highly diverse schools, so their schools would be more likely than others to be arbitrarily disrupted by a poorly designed formula.
Her boyfriend has moved in with her family and is holding down a full-time job at a bank.Most Latinos are enrolled in highly segregated schools, with few white classmates.
One study shows that employees of client companies who were enrolled and highly engaged in Vitality and had multiple chronic conditions had, in most cases, lower rates of hospital admission and shorter stays than people with the same conditions who were not participating as aggressively.
To investigate if TLR4 promoter variation might influence UTI susceptibility, we enrolled two highly selected, UTI prone study populations with a long history of either acute pyelonephritis (APN) or asymptomatic bacteriuria (ABU) in childhood (The clinical characteristics of patients and controls included in this study are provided in supplementary table 1 (Table S1)).
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