Selection bias is possible in the present research, in that only a certain kind of person will enrol in a study of this kind, implying that the results should not be generalized to the older population as a whole at this stage.
Furthermore, due to the nature of the studies, as with all meta-analyses of published data, we are not able to include data from AYA who, choose not to initiate medication despite eligibility, became lost to follow up or chose not to enrol into a study, or those deemed inappropriate for treatment by their physicians.
To enrol a participant, the study doctor will email/fax the consenting participant's name and date of birth to the administrative assistant.
In many countries, including India, only one parent/guardian's signature is legally required to enrol a child in a study.
From the assumption that 50% of the study participants would have LTBI, and the following targets: a 95% confidence level, a 5% degree of accuracy, a design effect of 1.5, 10% compensation for non-respondents, 10% compensation for exclusion during screening and 15% compensation for those participants lost to follow up; it was hoped to enrol a total of 713 study participants.
* as recognised by the identifaction and recruitment tool ** in % of the net sample *** of N = 200 (= target) In 13 smaller practices (<600 CTA-identified EPRs), the CTA tool identified fewer patients (5,061 vs. 11,006) than the 12 larger practices, but the practice staff was able to enrol a similar amount of study participants (753 vs. 773).
Then there is the simple matter of numbers: the rarer a cancer, the harder it is to enrol enough study participants from a minority population to gather statistically meaningful data.
This study will enrol a total of 600 eligible patients.
This corroborates a study that shows that trust affects participants' willingness to enrol in studies, and their tendency to tell the truth after joining studies [ 26].
Prisoners are allowed to enrol in study courses, and may partly receive funding from a charitable trust, but need to rely on each other for academic support.
