Sentence examples for enrichment difference from inspiring English sources

After haplogroup imputation, the ALTree method identified T1a1 in the T clade as differentially enriched in affected BRCA2 mutation carriers, whereas no enrichment difference was found for BRCA1 mutation carriers.

On the one hand, the reproducibility of the enrichment difference (near vs. far from genes) across at least three different platforms shows that our findings are not resulting from any pipeline-specific biases.

The optimization method features: (1) employing the block coordinate descent method to find the optimal solution in the space of enrichment difference parameters, (2) using scoping libraries to reduce the amount of CASMO-4 calculation, and (3) integrating a core critical constraint into the objective function that is used to quantify the quality of an axial enrichment design.

HOXD3 [Homoebox transcription factor] (chromosome # 2q31-37), a gene found to be methylated in lung cancer cell lines and primary tumours [34], which showed a distinct pattern of increasing methylation with tumour grade in our series based on average enrichment difference (6.4), suggesting that methylation of this gene may be involved in disease progression as well.

The objective of ALTree is to detect an enrichment difference at the level of the whole tree.

The fold enrichment difference in overlap between LCLs and control cells was calculated as the ratio between the proportions of case and control intervals that overlapped with VDR regions.

The segregation enrichment differences at different grain-boundary sites are explained in terms of atomic size and local hydrostatic stress.

ChIP-seq results on selected targets were validated by region-specific PCR and results were similar, i.e., no enrichment differences for any of the histone marks in the three different strains in any of the regions tested [data not shown (Seiboth et al. 2012)].

In order to capture significant differences in enrichment in each cancer cell line vs. normal osteoblast across shorter genomic regions (min. ∼350 nucleotides) with robust enrichment differences as well as intermediate (min. ∼500 nucleotides) and large regions (min. 1400 nucleotides), three HMM algorithms were applied (s-HMM, m-HMM, and l-HMM).

The differences in FO feeding-induced cardiac electrical remodeling between rabbit and pig models may be due to a combination of factors: differences in cellular and membrane environment of ion channels in cardiac myocytes which can impact the effects of n-3 PUFA enrichment, differences in gene regulation, and differences in the animal diets.

Thus, transcript abundance and GO term enrichment differences did not reflect ubiquitous seasonal or reproductive state variation, but rather SE-specific transcriptional regulation.