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To evaluate the chemotype enrichment, Korff et al. counted the discovered chemotypes within the enriched data set fraction with respect to the chemotype definition of Good and Oprea [35].
The reliability of these data was validated by the detection of known cell-specific transcripts and by expression in UNC-4 motor neurons of GFP reporters derived from the enriched data set.
In each table presented, probe sets were included only if gene expression was ≥200 in the enriched data set.
We then defined the genes that were common or unique to each cell strain from this enriched data set.
Similarly, 7 out of 8 (Table 3) GFP reporters for genes in the IVT-only neural enriched data set show expression in C. elegans neurons in vivo (Fig. 8).
Kaplan Meier curves for contralateral breast cancer from diagnosis were derived using the enriched data set with a confirmed FH or mutation: comparisons were made between no FH (sporadic): BRCA1; BRCand TP53; and FH but no mutation.
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DASMiner API was used to create enriched data sets of histone modification data and protein interactions by accessing multiple DAS sources.
We demonstrate how to assemble enriched data sets of histone modification and molecular interaction data by accessing different DAS sources using the API.
Microarray analysis from isolated floral organs [ 16] and pollen [ 34] revealed an overlap of 25 genes within the stamen-enriched data set.
The remaining transcripts probably arise from σA-independent transcription events occurring only under stress conditions since they were found in the total transcriptome library but not in the 5′-enriched data set.
To verify the rhizome-enriched expression of specific transcriptional regulators, we analyzed the expression patterns of 745 of the 777 rhizome-enriched data set using a custom oligonucleotide-based microarray (the other 32 genes did not yield good quality oligos for inclusion in the array).
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