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The area of tumour was manually micro-dissected to enrich the sample.
In order to enrich the sample, we therefore decided to include only patients with at least three chronic conditions.
Then, to enrich the sample, five proteins, which were most similar to the query protein by primary structure, were extracted from the KEGG SSDB database.
Second, the low rate of PTB in the Chinese population required us to retrospectively enrich the sample to increase the rate of PTB.
In order to enrich the sample with more severely depressed patients, all patients with a PHQ-8 score of 10 or more were invited to participate.
Individuals with a Short Physical Performance Battery score 8 ≤7 were preferentially enrolled (45% of the sample) to enrich the sample with individuals at high risk for major mobility disability.
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To enrich the samples for tumour cells, tissue specimens were obtained from the central part of the tumour specimens.
CD45 immunomagnetic depletion was performed for the purpose of triple-staining experiments only to enrich the samples with CTCs.
On the other hand, simulations at mixed/exchanged resolutions by parallel multi-scale approaches enrich the sampling of conformational space.
PCR amplification with 15 cycles using Phusion polymerase was performed with primers complementary to the adapter sequences to enrich the samples for the desired fragments.
In order to enrich the samples for neoplastic cells, normal tissue was removed from the samples using macro-dissection based on the frozen section histology.
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