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Overlapping gene organization would provide some degree of protection from genome decay, as long as the function of the protein encoded by the overlapping counterpart is important enough to be maintained through natural selection.
It should also tell us what are the ancestral regulations that were robust enough to be maintained in cnidarians and vertebrates.
The first is that the effects of CBT-AD on depression were not robust enough to be maintained over time relative to alerting providers of depression diagnoses.
Further, the most difficult problem is that these small siRNA/shRNA agents are not stable enough to be maintained at an optimal dose in vivo due to the abundant RNase activities in higher vertebrates (Brantl 2002).
This seemingly paradoxical finding indicates that a certain small subset of patients possibly exist, in whom biologic therapy was useful for induction of remission - deep enough to be maintained later-on independent of a pharmacokinetic/immunogenicity problem that later arose.
This may not be necessary, however, for localizing histone modifications or for simply determining nucleosome positioning, because the histone-DNA interactions are generally strong enough to be maintained without using a cross-linking agent, and in this case a native ChIP (n-ChIP) without cross-linking might be preferable [ 1].
Similar(54)
Enough residence time is to be maintained so that entire coal will be collected and separated.
This low-dose parasitaemia has to be maintained for enough time to stimulate the asexual-stage immune response.
Moreover, the frame should be maintained long enough to prevent secondary loss of fracture reduction.
He claims Transport for London is not doing enough to ensure standards are maintained.
The filament was applied to the skin with enough pressure to buckle and was maintained for up to six seconds.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com