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Most of the other families lost in vertebrates and mammals could not be correlated with clear loss of functionality, either because not enough functional information was available for the considered genes or because the same functionality was replaced by other genes in mammals and vertebrates.
This maturation function is particularly needed under oxidative conditions to generate enough functional Rli1 to support normal growth.
Thus, while histone storage and exchange in early development represents a critical function of nucleoplasmin, the appearance of SNBPs of the H-type early in metazoan evolution, as well as their subsequent differentiation towards PL and P-types, could have been a strong enough functional constraint to recruit SNBP removal as an acquired non-specific function.
"There are not enough functional mortuaries to take them.
NB84 treatment restored enough functional α-l-iduronidase activity to partially reverse abnormal GAG accumulation and lysosomal abundance in mouse embryonic fibroblasts derived from the Idua-W392X mouse.
For conserved metabolic pathways such as glycolysis and the TCA cycle, such an approach is necessary in order to capture enough functional diversity within candidate genes.
Similar(31)
They make every package by hand, so it took seven prototypes to get to one that was sturdy enough, discrete, functional, and doable in under four minutes.
Prospectively, similar successes in humans could be directly linked to the feasibility of obtaining enough fully functional spermatogonial stem cells from minimal testis biopsies to be therapeutically effective.
Interestingly enough, significant functional impairments were found in the absence of neuropathy too.
If these paralogs are retained for enough time, functional constraints presumably would increase to a pre-WGD level.
These disadvantages were sidestepped by using raw carbon as starting material and a one-step ultrasonic treatment in a hydroxide peroxide solution [ 24], which produced enough active functional groups for covalent attachment.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com