To find the global peak on the rugged landscape, the adaptive walk requires enormous sequence diversity.
The direct computational method for the prediction of secondary structures in long RNA sequences, such as large introns, is not feasible because of the enormous sequence length [27].
Additional file 40 shows all of the Syt proteins of N. vectensis, demonstrating enormous sequence variation.
Substantial sequence diversity was obtained for many protein families, owing to the enormous sequence space of TrEMBL.
Massively parallel sequencing of cDNA is now an efficient route for generating enormous sequence collections that represent expressed genes.
Given the enormous sequence data available, the authors don't have to limit themselves by only experimentally studied retrotransposons.
Most AMPs are cationic polypeptides, usually smaller than 100 amino acids in length, with enormous sequence diversity.
These Next-Generation Sequencing (NGS) libraries have an enormous sequencing depth and better effectiveness, producing at least 100 to 10,000 times higher throughput than classical Sanger sequencing [ 23].
The HLA region is highly polymorphic with enormous sequence diversity and gene density, and the genes are in extensive linkage disequilibrium.
However, with the enormous sequencing output from current sequencing platforms, generating a sufficient number of amplicons across an appropriate number of samples to avoid unreasonable sequencing depth and cost is prohibitive.
