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Standing near its entrance, next to the enormous sample of banded iron she collected, she rests manicured hands on the black boulder streaked with burnt red and tells its story.
Mining the resulting terabyte or so of data will allow astronomers to investigate the evolution of galaxies, for example, since the SDSS will provide an enormous sample of them.And even the SDSS will represent only a single snapshot of the sky.
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On the other hand, the enormous sample size of pooled studies may amplify even the small individual effects, for example, due to platform effects, population strata, or genotyping batch effects, resulting in false positive findings, as heterogeneity between studies is amplified by imputation.
We would again expect variations on the sensible theme of fire fighting such as these to produce very tiny differences in outcomes, meaning we would need an enormous sample, a lot of time, and a lot of money to append this bit of specificity to the fundamentals we already knew.
Although randomised controlled trials are a powerful method of showing vaccine efficacy, an enormous sample size is required because of the current low morbidity from pneumococcal pneumonia.
Disentangling the relative contributions of genetic and environmental factors to the mechanism of a complex human disease such as MetS is daunting because of the expense of procuring the enormous sample sizes necessary to make statistically valid conclusions, particularly in the face of tremendous genetic and lifestyle variation.
This enormous sample size outweighs the disadvantage of plot-level increases in uncertainty when it comes to estimating uncertainty in the mean.
The P-criterion implies that an enormous sample size is required to identify a pathogenic variant of the average mutation rate.
The CPS and ACS feature in-person interviews, enormous sample sizes and very high response rates, making them some of the most reliable surveys available.
In an ideal world, we would have a randomized trial with the enormous sample necessary to answer this question as well as decades of follow-up.
would require an enormous sample which may not be feasible.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com