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Both goblet cell metaplasia and bronchial gland enlargement lead to airway mucus hypersecretion, which contributes to airway obstruction [ 6].
In the case of asthma, goblet cells become hyperplastic, and a high proportion of goblet cells and submucosal gland enlargement lead to mucus hypersecretion and contribute significantly to airflow limitation [ 6, 29].
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For these reasons, NATO's policy of partnership and outreach will continue, moving on from dialogue and confidence-building to practical, operational issues.Nor has NATO's enlargement led to the isolation of Russia that many feared.
A case report by Horger et al. [ 6] presented a case of a 32-year-old woman whose elevated CA-125 level and right ovarian enlargement led to an incorrect presumptive diagnosis of ovarian carcinoma with peritoneal carcinomatosis.
Progressive cyst expansion leads to massive enlargement and distortion of the kidney's architecture and, ultimately, to ESRD in most patients [ 3].
However, the presence of tunnel enlargement may lead to increased knee laxity or worse clinical outcome in the longer follow-up.
The presence of tunnel enlargement may lead to increased knee laxity or worse clinical outcome in the longer follow-up although it is insignificant in the short term (Buelow et al., 2002; Clatworthy et al., 1999; Fules et al., 2003; L'Insalata et al., 1997; Webster et al., 2001).
Aberrant activation of Akt signaling gives rise to pathological cardiac remodeling including hypertrophy and heart enlargement that leads to heart failure [24], [25], [26], [27], [28], [29].
The enlargement usually leads to lower urinary tract symptoms, 1 irrespective of whether it is benign or malignant.
Dilated cardiomyopathy (DCM) is the most common type of non-ischemic cardiomyopathy, and is characterized by myocardial contractile dysfunction and cardiac diameter enlargement, which leads to heart failure.
E5 and E6 act early in transformation (before integration) and are known to disrupt cytokeratin-causing perinuclear cytoplasmic clearing and nuclear enlargement, which leads to the appearance of a koilocyte (Krawczyk et al, 2008).
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