Surprisingly, in 5 of the cases the region of low uptake had become further enlarged, indicating progression.
Specifically, the promoter leakage makes the burst size be reduced and the burst frequency be enlarged, indicating that the promoter leakage makes the gene produce fewer bursts.
In that study, the number of spermatids per testis was decreased by TCDD treatment, and the spaces between adjacent Sertoli cells were enlarged, indicating dissolution of the germinal epithelium.
Within two hours of inhibiting kinase activity by staurosporine, the SR45/U1-70K was reorganized into irregularly shaped enlarged speckles indicating that the subcellular localization of this complex is regulated by phosphorylation (Figure 6).
Further, by microscopy we observed that cells exposed to HNP 1-3 appeared more diffuse and had enlarged nuclei, indicating apoptosis (FIG. 4A&B).
Disruption of endogenous SETD8, accompanied by suppression of H4K20 monomethylation, leads to cell cycle defects, chromatin decondensation, and enlarged nuclei, indicating the essential role(s) of SETD8 in DNA replication.
The arrow within the enlarged image indicates lipomatous degeneration of the right semimembranosus muscle.
For different marriage cohorts, the slope of the divorce risk function gradually enlarges, which indicates that as time goes on, the rate of divorce for the divorced couples has increased considerably.
Morphometric analysis of single cardiac myocytes demonstrated 59% enlarged myocytes and 58% enlarged nuclei, both indicating cellular hypertrophy and explaining muscle hypertrophy at least in part (see Figure 1C).
Furthermore, various indices of diastolic dysfunction were abnormal (e.g. an E/A ratio <1 or an enlarged left atrium) indicating impaired LV compliance.
