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In contrast to the coherent biclusters generated by most methods, an ENIGMA expression module may contain distinctive subpatterns.
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A fourth advantage that is more obvious on real data is the use of ENIGMA's expression module concept for biological discovery.
ENIGMA leverages differential expression analysis results to extract expression modules from perturbational gene expression data.
The Missa Solemnis is an enigma: a sparkling expression of faith that is at the same time riven with doubt, ambiguity and darkness.
Except me". The Missa Solemnis is an enigma: a sparkling expression of faith that is at the same time riven with doubt, ambiguity and darkness.
One of the enigmas of gene expression regulation is the apparent lack of correlation between the changes at the mRNA level and the protein level in some systems.
Whole passages of non-event stream by, and you half want to scream, and yet — damn it all — by the end of "The New World" the spell of the images, plus the enigma of Kilcher's expression (she is as sculpted as an idol, and every bit as amenable to worship), somehow breaks you down.
Finally, we apply ENIGMA to the Rosetta compendium of expression profiles for Saccharomyces cerevisiae and we analyze one pheromone response-related module in more detail, demonstrating the potential of ENIGMA to generate detailed predictions.
Briefly, ENIGMA takes as input a set of perturbational expression data, externally calculated p-values for differential expression (e.g. using the limma package in Bioconductor [ 29]) and other data types if available.
In the images in global circulation, grabbed from a Guardian video, he avoids the one facial expression that might undermine his enigma: he doesn't smile.
Following this approach, other repeats can be used to excavate further the tagged transcripts in different species for their comparative organization and expression, which would assist resolving the enigma of such simple sequence repeats in the mammalian genome.
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