Compared to the wild type, both split variants increased the thermostability by 11 °C and Split178 enhanced the turnover number and catalytic efficiency by 1.15-fold and 1.66-fold, while Split166 decreased these parameters by 3.2-fold and 5-fold, respectively.
A recent study has shown that Type I IFN signaling on splenic CD8+ DCs, in particular, enhances the turnover of these cells in vivo [55].
In addition, autophagy enhances the turnover of aggregate-prone cellular proteins, thus reducing the abundance of potent neurotoxic factors including, but not limited to, huntingtin aggregates [ 131].
It was proposed that this adduct can act as radical site that enhances the turnover of oxyferrous (compound III-like) heme and avoids release of superoxide [12].
Similar results have previously been observed by Mahan et al. when they demonstrated that the D314S mutation in CodA of E. coli enhanced the turnover ratio of 5-fluorocytosine/cytosine by 4-fold.
Hambleton (1993) has noted that the toxin also enhances the ongoing turnover of NMJs, thus initiating physical recovery before full functional recovery.
Pulses, and legumes in general, can play an important role in agriculture because their ability to biologically fix atmospheric nitrogen and to enhance the biological turnover of phosphorous; thus they could become the cornerstone of sustainable agriculture in Africa.
However, if D. melanogaster females would reproduce early in their life, the weak female bias in the number of germ-cell divisions could enhance the SSR turnover in the X chromosome and thus cause a slightly faster SSR loss.
Increasing the ratio of silica to collagen (0.25, 0.5, 0.75, 1.0, 1.55, 1.5 and 2.0 w/w) gave a marked advantage in terms of improving the water uptake and compressive modulus of the CS scaffolds, while also enhancing the biological stability and the turnover time.
