Sentence examples for enhancing specificity from inspiring English sources
Hox transcription factors can co-operatively bind with PBC-class co-factors, enhancing specificity and affinity for their appropriate binding sites.
For example, oligonucleotides can be synthesized such that homologous sequences between genes can be excluded, thereby enhancing specificity.
This allowed direct comparisons between two sharply delineated groups (MHC Yes versus MHC No), enhancing specificity of MHC status classification.
Our data substantiate the applicability of Tev-mTALENs as genome-editing tools but highlight DNA spacer and cleavage site nucleotide preferences that, while enhancing specificity, do confer moderate targeting constraints.
In contrast to FokI, use of a monomeric nuclease with some sequence specificity such as I-Tev1 might represent a further improvement, enhancing specificity by introducing moderate targeting requirements beyond those of the single TALE domain.
Another approach to enhancing specificity would be to focus surveillance on the severe phases of disease, since the category A bioterrorism infections are more likely than many common infections to progress to life-threatening illness.
Our design comprised de novo synthetic cancer-specific promoters and, to enhance specificity, an RNA-based AND gate that generates combinatorial immunomodulatory outputs only when both promoters are mutually active.
Furthermore, a melanoma specific promoter was used to enhance specificity of the DNA-delivery strategy.
These proteins likely include phosphoproteins that bind directly to 14-3-3s 14-3-3s 14-3-3sbind indirectly to 14-3-3s as comproteinsof multhatubindt complexes and proteindirectlyave been isolatod 14-3-3s 14-3-3s 14-3-3sh the HT experiments use strasegies to enhancomponentscity).
All the mutants show enhanced specificity constants for CB1954, and, apart from N71S, the enhancement is selective for CB1954 over nitrofurazone.
These features are useful to combat relapse, mitigate over-activation, and enhance specificity.
