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It has been recently reported that a gain of function-mutation in the human DYRK1B gene exacerbates metabolic syndrome by enhancing obesity.
By positional cloning, we recently identified Tbc1d1 in the obesity QTL Nob1 that reduces fatty acid oxidation in muscle, thereby enhancing obesity and diabetes susceptibility (10).
Appetitive food mechanisms in the brain for example stimulate a greater desire for "junk" food after sleep deprivation, thus potentially enhancing obesity [ 70].
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Efforts should target enhanced obesity diagnosis as a first step toward improving pediatric obesity management.
The age-adapted techniques have the potential to enhance obesity programs in a population for whom the obesity issue is critical.
A question that remains unanswered is whether CHWs can enhance obesity prevention outcomes above and beyond what can be achieved through primary care.
There is a need to investigate the impact of these psychological factors on food intake and food choice under stress, in order to enhance obesity prevention and intervention efforts [ 22].
If a simpler, more practical alternative to BMI was available this may increase clinical assessments of obesity, and enhance obesity surveillance in resource-poor settings where data on the prevalence of overweight and obesity among older children and adolescents are sparse.
Collectively, these results demonstrate that CB2 receptors enhance obesity-associated insulin resistance.
The second explanation is that the production of adipokines by fat tissue, such as IL-6 and tumor necrosis factor-α, enhances obesity-induced inflammation [ 22].
31 In order to begin improving obesity care, medical education should focus on enhancing those obesity-related skills PCPs feel most qualified to deliver as well as changing the composition of healthcare teams and practice resources.
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